Effector profile
PlantPEAD ID: PlantPEAD00871 Uniprot ID: A0A5B0N367 Source: Article
Localization: Cytoplasmic(Exp) Pathogen taxonomy ID: 5297 Pathogen type: Fungi
Species: Puccinia graminis Strain: f. sp. tritici 21-0 Other name: Black stem rust fungus
Gene name: AvrSr35 NCBI Gene ID: VSWC01000119
Entry name: A0A5B0N367_PUCGR Protein name: Avirulence factor
DOI: 10.1038/s41586-022-05231-w; 10.1094/MPMI-08-21-0201-R
Gene/Protein information
Gene sequence:
CCATCCTGCCTGACCAGATTAGTCAGTCCTCACAGACTGATTCAACATAAATAGAGGCCCTCCTTAACATTAGACAATTCTTCCACATCACCTGACACACTTCCTACATAGATACCTGTTCAAACTAAAGATATTTATTTTCATTCCAACCTATCAATCTTCACATCATCCCATCAACCAACATGTCACATCACTTTGGATTACGTAAAATAAAACTACTGATTTTGCTCTTCCTTCAAGTTCATGGGAGTCAATGTGCCATGAGGAACTTTGCTGCAGATAGAGTCCATGGGGTAGAATCAGTCATTTCCGGGTCCAAGAGCTCATCTAATCCCATGGCACTGTCTAAGTCCATGGATAAACCAGACACATCTGATTTGGTAGATTCAAATGTTCAGGCAAAAAATGATGGGAGCAGATATGAAGAAGATTTTACAGCTAAATATTCTGAGCAAGTAGATCATGTTTCTAAGATCCTAAAAGAGATTGAAGAACAAGAGCCTGGAACTATAATTATTGATCATAAAGCATTCCCAATCCAAGACAAATCACCAAAACAGGTGGTTAATTTCCCTTTTCCAAAAAAGATGATTACAGAATCTAATTCAAAAGACATCAGAGAATATCTTGCAAGCACATTTCCTTTTGAACAGCAATCAACTATATTAGACAGTGTGAAATCAATTGCCAAAGTACAAATAGATGACCGAAAGGCATTTGATCTTCAATTGAAATTCAGACAGGAAAACCTGGCAGAACTCAAGGATCAAATTATACTTTCACTGGGTGCAAATAATGGAAATCAAAACTGGCAAAAGTTACTTGATTACACAAATAAGTTGGATGAATTGAGCAACACCAAAATTTCCCCTGAAGAATTTATTGAGGAGATTCAAAAGGTATTGTACAAGGTCAAATTGGAATCTACATCAACATCCAAGCTTTACAGTCAATTTAATCTATCAATTCAAGATTTTGCACTTCAAATAATTCATTCAAAATACAAGTCAAATCAAATAAGTCAAAATGATCTTTTGAAGTTGATCACAGAGGATGAGATGCTAAAAATTCTGGCAAAGACCAAGGTTCTCACCTACAAGATGAAATATTTTGATTCAGCATCAAAAATGGGAATCAATAAATATATCAGTACTGAGATGATGGACCTGGACTGGCAATTTTCACATTATAAGACTTTCAATGATGCTTTGAAAAAAAATAAAGCAAGTGATTCAAGCTATCTTGGATGGCTAACCCATGGGTATTCTATCAAATACGGATTATCTCCTAATAATGAAAGGAGTATGTTTTTCCAAGATGGAAGAAAATATGCTGAATTGTATGCATTTTCTAAAAGTCCCCACAGGAAAATAATACCTGGGGAGCACCTCAAAGATCTGTTAGCTAAAATCAATAAATCCAAAGGTATTTTTCTGGATCAGAATGCCTTGCTAGATAAAAGGATCTATGCATTTCATGAGTTGAACACTCTTGAAACACATTTTCCAGGAATAACTTCATCTTTTACGGATGATTTGAAATCAAATTACCGCAAGAAGATGGAATCTGTTTCTCTCACATGCCAGGTTCTTCAAGAAATTGGCAACATTCACCGGTTCATTGAATCTAAAGTCCCATATCACAGTTCCACAGAATATGGATTGTTTTCTATCCCCAAGATATTTTCAATCCCAATCGATTATAAGCATGGAGAAAAGGAGAATTTGGTCTCCTATGTTGACTTTCTTTACTCCACTGCTCATGAAAGAATTCTCCAGGATAATTCAATTAATCAACTTTGCCTTGACCCATTACAAGAATCCTTAAACCGTATTAAAAGCAATATACCTGTTTTCTTCAACTTAGCTTCCCATAGTTCACCAATCAAGCCATCCAATGTTCATGAAGGCAAATTGTGATGTTTTTTTTTACTTCATAATTCAAATATTTTCTTTTTCTTTTTCTTCTGCTCATTCTTTTACTATCAAGAAAGTTCATTCCTTGTGTGTTAAATCCTTTTATCATAAGAATAATCAAATCATGTTCAAGCAAAATTCCATTATATTCAATCCAGAAACATTTGATTGACCATTGAAATCATCCAATTTTCTTGGAGTTGATTTATGACTGAATTCATTTCCTTAATCATTTGAATTTGTTTCCTGAATTCTTCTTCTTTTCATTTTTTCTTTCAAGAAAATTTCCATTATTAGGGGGTATCAAATATAGGAAATCCACCATCAGAAACCAGTCACTTTTCTAAAAACTTTTTTTTGCATAAATGGGCCCCAAAAGGGGTTAAATGGATAACCAACATGTTTAAAAAAGGGTGGATTTTTTCAAACCAGTCAATTAATTAATGGTGGATTTGGTTATATTTGATACCCCCTATTTTTGATTTTTATCTTATCATTTTATCCAAATACCCAAGAAGAAAAAAAAAGAATGGAAG
Protein sequence:
MSHHFGLRKIKLLILLFLQVHGSQCAMRNFAADRVHGVESVISGSKSSSNPMALSKSMDKPDTSDLVDSNVQAKNDGSRYEEDFTAKYSEQVDHVSKILKEIEEQEPGTIIIDHKAFPIQDKSPKQVVNFPFPKKMITESNSKDIREYLASTFPFEQQSTILDSVKSIAKVQIDDRKAFDLQLKFRQENLAELKDQIILSLGANNGNQNWQKLLDYTNKLDELSNTKISPEEFIEEIQKVLYKVKLESTSTSKLYSQFNLSIQDFALQIIHSKYKSNQISQNDLLKLITEDEMLKILAKTKVLTYKMKYFDSASKMGINKYISTEMMDLDWQFSHYKTFNDALKKNKASDSSYLGWLTHGYSIKYGLSPNNERSMFFQDGRKYAELYAFSKSPHRKIIPGEHLKDLLAKINKSKGIFLDQNALLDKRIYAFHELNTLETHFPGITSSFTDDLKSNYRKKMESVSLTCQVLQEIGNIHRFIESKVPYHSSTEYGLFSIPKIFSIPIDYKHGEKENLVSYVDFLYSTAHERILQDNSINQLCLDPLQESLNRIKSNIPVFFNLASHSSPIKPSNVHEGKL*
Protein structure:
PDB(X-ray)(7XDS)
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Main properties of effector
Molecular weight Sequence length Theoretical pI GRAVY Instability index
66377.6 579 8.3 -0.503 41.17
Plant infestation information
Experimental plant:
Susceptible plant: Triticum aestivum Disease name: Stem rust
Host classification: Monocots NCBI Species: 4565
Pathogen-plant protein interaction
Uniprot ID Protein name Gene name Species Protein sequence
S5ABD6
CNL9
Sr35
Triticum monococcum subsp. monococcum
MEIAMGAIGSLLPKLGELLIGEITLEKKVRKGIESLITELKLMQAVLSKVSKVPADQLDEGVKIWAGNVKELSYQMEDIVDAFMVRVGDGGESTNPKNRVKKILKKVKKLFKNGKDLHRISAALEEVVLQAKQLAELRQRYEQEMRDTSANTSVDPRMMALYTDVTELVGIEETRDKLINMLTEGDDWSKHPLKTISIVGFGGLGKTTLAKAAYDKIKVQFDCGAFVSVSRNPEMKKVLKDILYGLDKVKYENIHNAARDEKYLIDDIIEFLNDKRYLIVIDDIWNEKAWELIKCAFSKKSPGSRLITTTRNVSVSEACCSSEDDIYRMEPLSNDVSRTLFCKRIFSQEEGCPQELLKVSEEILKKCGGVPLAIITIASLLANKGHIKAKDEWYALLSSIGHGLTKNRSLEQMKKILLFSYYDLPSYLKPCLLYLSIFPEDREIRRARLIWRWISEGFVYSEKQDISLYELGDSYFNELVNRSMIQPIGIDDEGKVKACRVHDMVLDLICSLSSEENFVTILDDPRRKMPNSESKVRRLSIQNSKIDVDTTRMEHMRSVTVFSDNVVGKVLDISRFKVLRVLDLEGCHVSDVGYVGNLLHLRYLGLKGTHVKDLPMEIGKLQFLLTLDLRGTKIEVLPWSVVQLRRLMCLYVDYGMKLPSGIGNLTFLEVLDDLGLSDVDLDFVKELGRLTKLRVLRLDFHGFDQSMGKALEESISNMYKLDSLDVFVNRGLINCLSEHWVPPPRLCRLAFPSKRSWFKTLPSWINPSSLPLLSYLDITLFEVRSEDIQLLGTLPALVYLEIWNYSVFEEAHEVEAPVLSSGAALFPCATECRFIGIGAVPSMFPQGAAPRLKRLWFTFPAKWISSENIGLGMRHLPSLQRVVVDVISEGASREEADEAEAALRAAAEDHPNRPILDIW