Effector profile
PlantPEAD ID: PlantPEAD01029 Uniprot ID: G3C9M1 Source: Article
Localization: Cytoplasmic(Exp) Pathogen taxonomy ID: 272952 Pathogen type: Oomycota
Species: Hyaloperonospora arabidopsidis Strain: strain Emoy2 Other name: Peronospora arabidopsidis
Gene name: HARXL10 NCBI Gene ID: HE574719
Entry name: G3C9M1_HYAAE Protein name: RxLR effector candidate
DOI: 10.1126/science.1203659
Gene/Protein information
Gene sequence:
ATGGCCTCGGGACTCGCGAAACTAGGGGCTGCGACACAAGGTGCTCATGAACTCGAGGACGAGACATCAGGAAGACTTCTGAGGGTGCACACTTCTGCAAAGGAAGATCAAGAAGGTCGAATGATTCCTGGATCCGAGTTTTTTGAAAAGGCCCAGCCCGTCCTTCACAACTTGTCTATCAACATGCCGAACCTGGACGAAATCAAAGCGAATGCTGCCAGTTATTTTTACTTGTGTATGCGTGACGTGCTTCTGACAGAACAACAGCGTATCAAGGCATTTAACGATATGCGACGGAGAGCTGTGGTCGAGAGACTTCAAAGTATCCAGCCTATCGATTGGAACGTGGGGGCAGTCGATTGGCAGGCCATGCTCGCGTTGCAAAATCTTCTAGAGAACCGTGACATGTACTATCTGGCGATCTCACTGGCACTGGCAAAGCAGCCGTCAGTTCTCATACCGGAGCCGATTGCTAGAACGGCTAAGGAGATGGAATTGTCGCAATTCGGCTTGTGGGCATCGATGGAAAAGGTTCCCGAAGTAGTAAGAGAGCAACTTAAGAAGTTGCCCGACTTTGTTCAAGCCGCCGGTGATCATGCCCTCGTAAATGAGGTGGTACACAGCTACAAGCAGTTTTCCTCCGCTCTAATGCGTAAAAAAGCGTAA
Protein sequence:
MASGLAKLGAATQGAHELEDETSGRLLRVHTSAKEDQEGRMIPGSEFFEKAQPVLHNLSINMPNLDEIKANAASYFYLCMRDVLLTEQQRIKAFNDMRRRAVVERLQSIQPIDWNVGAVDWQAMLALQNLLENRDMYYLAISLALAKQPSVLIPEPIARTAKEMELSQFGLWASMEKVPEVVREQLKKLPDFVQAAGDHALVNEVVHSYKQFSSALMRKKA
Protein structure:
AlphaFold
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Main properties of effector
Molecular weight Sequence length Theoretical pI GRAVY Instability index
24792.5 221 6.26 -0.26 41.72
Plant infestation information
Experimental plant: Arabidopsis thaliana (related: thale cress)
Susceptible plant: Arabidopsis thaliana Disease name: Downy mildew of Arabidopsis
Host classification: Eudicots NCBI Species: 3702
Pathogen-plant protein interaction
Uniprot ID Protein name Gene name Species Protein sequence
Q9LVI4
Protein TIFY 6B
TIFY6B
Arabidopsis thaliana (related: thale cress)
MERDFLGLGSKNSPITVKEETSESSRDSAPNRGMNWSFSNKVSASSSQFLSFRPTQEDRHRKSGNYHLPHSGSFMPSSVADVYDSTRKAPYSSVQGVRMFPNSNQHEETNAVSMSMPGFQSHHYAPGGRSFMNNNNNSQPLVGVPIMAPPISILPPPGSIVGTTDIRSSSKPIGSPAQLTIFYAGSVCVYDDISPEKAKAIMLLAGNGSSMPQVFSPPQTHQQVVHHTRASVDSSAMPPSFMPTISYLSPEAGSSTNGLGATKATRGLTSTYHNNQANGSNINCPVPVSCSTNVMAPTVALPLARKASLARFLEKRKERVTSVSPYCLDKKSSTDCRRSMSECISSSLSSAT
Q9C9L2
Transcription factor TCP15
TCP15
Arabidopsis thaliana (related: thale cress)
MDPDPDHNHRPNFPLQLLDSSTSSSSTSLAIISTTSEPNSEPKKPPPKRTSTKDRHTKVEGRGRRIRMPAMCAARVFQLTRELGHKSDGETIEWLLQQAEPAVIAATGTGTIPANFTSLNISLRSSRSSLSAAHLRTTPSSYYFHSPHQSMTHHLQHQHQVRPKNESHSSSSSSSQLLDHNQMGNYLVQSTAGSLPTSQSPATAPFWSSGDNTQNLWAFNINPHHSGVVAGDVYNPNSGGSGGGSGVHLMNFAAPIALFSGQPLASGYGGGGGGGGEHSHYGVLAALNAAYRPVAETGNHNNNQQNRDGDHHHNHQEDGSTSHHS
Q8LAZ7
COP9 signalosome complex subunit 5a
CSN5A
Arabidopsis thaliana (related: thale cress)
MEGSSSAIARKTWELENNILPVEPTDSASDSIFHYDDASQAKIQQEKPWASDPNYFKRVHISALALLKMVVHARSGGTIEIMGLMQGKTEGDTIIVMDAFALPVEGTETRVNAQSDAYEYMVEYSQTSKLAGRLENVVGWYHSHPGYGCWLSGIDVSTQMLNQQYQEPFLAVVIDPTRTVSAGKVEIGAFRTYPEGHKISDDHVSEYQTIPLNKIEDFGVHCKQYYSLDITYFKSSLDSHLLDLLWNKYWVNTLSSSPLLGNGDYVAGQISDLAEKLEQAESQLANSRYGGIAPAGHQRRKEDEPQLAKITRDSAKITVEQVHGLMSQVIKDILFNSARQSKKSADDSSDPEPMITS
Q9FTA2
Transcription factor TCP21
TCP21
Arabidopsis thaliana (related: thale cress)
MADNDGAVSNGIIVEQTSNKGPLNAVKKPPSKDRHSKVDGRGRRIRMPIICAARVFQLTRELGHKSDGQTIEWLLRQAEPSIIAATGTGTTPASFSTASLSTSSPFTLGKRVVRAEEGESGGGGGGGLTVGHTMGTSLMGGGGSGGFWAVPARPDFGQVWSFATGAPPEMVFAQQQQPATLFVRHQQQQQASAAAAAAMGEASAARVGNYLPGHHLNLLASLSGGANGSGRREDDHEPR
O81851
E3 ubiquitin-protein ligase BOI
BOI
Arabidopsis thaliana (related: thale cress)
MAVQAHHMNIFSQFISPNRDCVKFQENMNHGEFEFTGGEVPLITGESFAVEPLAAKANFNKAESGLSYNFTVPPLSTKRQRDFQFSDSNAPVKRRSVAFDSSSPSLINVELVSQIQNQQQSEIDRFVAQQTEKLRIEIEARQQTQTRMLASAVQNVIAKKLKEKDDEIVRIRNLNWVLQERVKSLYVENQIWRDIAQTNEANANTLRTNLDQVLAQLETFPTASAVVEDDAESSCGSCCGDGGGEAVTAVGGGCKRCGEREASVLVLPCRHLCLCTVCGGSALLRTCPVCDMVMNASVHVNMSS
O22768
Transcription factor UNE12
UNE12
Arabidopsis thaliana (related: thale cress)
MASNNPHDNLSDQTPSDDFFEQILGLPNFSASSAAGLSGVDGGLGGGAPPMMLQLGSGEEGSHMGGLGGSGPTGFHNQMFPLGLSLDQGKGPGFLRPEGGHGSGKRFSDDVVDNRCSSMKPVFHGQPMQQPPPSAPHQPTSIRPRVRARRGQATDPHSIAERLRRERIAERIRALQELVPTVNKTDRAAMIDEIVDYVKFLRLQVKVLSMSRLGGAGAVAPLVTDMPLSSSVEDETGEGGRTPQPAWEKWSNDGTERQVAKLMEENVGAAMQLLQSKALCMMPISLAMAIYHSQPPDTSSVVKPENNPPQ
Q9LPR8
Scarecrow-like protein 3
SCL3
Arabidopsis thaliana (related: thale cress)
MVAMFQEDNGTSSVASSPLQVFSTMSLNRPTLLASSSPFHCLKDLKPEERGLYLIHLLLTCANHVASGSLQNANAALEQLSHLASPDGDTMQRIAAYFTEALANRILKSWPGLYKALNATQTRTNNVSEEIHVRRLFFEMFPILKVSYLLTNRAILEAMEGEKMVHVIDLDASEPAQWLALLQAFNSRPEGPPHLRITGVHHQKEVLEQMAHRLIEEAEKLDIPFQFNPVVSRLDCLNVEQLRVKTGEALAVSSVLQLHTFLASDDDLMRKNCALRFQNNPSGVDLQRVLMMSHGSAAEARENDMSNNNGYSPSGDSASSLPLPSSGRTDSFLNAIWGLSPKVMVVTEQDSDHNGSTLMERLLESLYTYAALFDCLETKVPRTSQDRIKVEKMLFGEEIKNIISCEGFERRERHEKLEKWSQRIDLAGFGNVPLSYYAMLQARRLLQGCGFDGYRIKEESGCAVICWQDRPLYSVSAWRCRK