Pine wilt disease

Nematodes carried by adult sawyer beetles start the infestation inside pine tree branches through spring feeding activities. After the introduction, the nematodes rapidly reproduce into tremendous numbers, eventually clogging the tree’s vascular system. This disrupts the plant’s water flow and stops branches from producing resin, a substance trees produce in response to injury. By mid-summer, needles will have turned brown and the entire tree eventually becomes brittle and dies. As the tree declines, sawyer beetle pupae inside the declining trees become infected with nematodes. After overwintering inside the tree, the pupae produce nematode infected adults in the spring that spread the disease to new trees.

List of experimentally identified pathogen effectors

PlantPEAD ID Uniprot ID Localization Gene name Pathogen type Infested plant Species
A0A1I7RYM0
Apoplastic(Exp)
BxSapB1 (BXY_0583800)
Nematoda
Pinus thunbergii
Bursaphelenchus xylophilus
A0A1I7RW40
Apoplastic(Pre)
SapB3 (BXY_0495300)
Nematoda
Pinus thunbergii
Bursaphelenchus xylophilus
Showing 1 to 2 of 2

List of orthologous identified pathogen effectors

PlantPEAD ID Uniprot ID Localization Pathogen type Species Query proteins
A0A811K294
Cytoplasmic(Pre)
Nematoda
Bursaphelenchus okinawaensis
A0A1I7RYM0
A0A811K0K8
Cytoplasmic(Pre)
Nematoda
Bursaphelenchus okinawaensis
A0A1I7RW40
A0A811K262
Cytoplasmic(Pre)
Nematoda
Bursaphelenchus okinawaensis
A0A1I7RW40
Showing 1 to 3 of 3