Late blight

Late blight is caused by the fungal-like oomycete pathogen Phytophthora infestans. The primary host is potato and tomato. The first symptoms of late blight in the field are small, light to dark green, circular to irregular-shaped water-soaked spots. These lesions usually appear first on the lower leaves. Lesions often begin to develop near the leaf tips or edges, where dew is retained the longest. During cool, moist weather, these lesions expand rapidly into large, dark brown or black lesions, often appearing greasy. Leaf lesions also frequently are surrounded by a yellow chlorotic halo. The lesions are not limited by leaflet veins, and as new infections occur and existing infections coalesce, entire leaves can become blighted and killed within just a few days. The lesions also may be present on the petioles and stems of the plant. During active growth, especially in cool, wet weather, a white mildew-appearing area is visible at the edge of the lesions or along petioles. This is the area where the late blight pathogen actively produces spores. As the weather changes to warm and dry, these lesions become dry, stop sporulating and become tan.

List of experimentally identified pathogen effectors

PlantPEAD ID Uniprot ID Localization Gene name Pathogen type Infested plant Species
D0N4Y1
Cytoplasmic(Exp)
PexRD18(PITG_06478)
Oomycota
Solanum lycopersicum, Solanum tuberosum
Phytophthora infestans
D0N5L4
Cytoplasmic(Exp)
PexRD49(PITG_05750)
Oomycota
Solanum lycopersicum, Solanum tuberosum
Phytophthora infestans
D0N607
Cytoplasmic(Exp)
CRE4(PITG_05910)
Oomycota
Solanum lycopersicum, Solanum tuberosum
Phytophthora infestans
D0N6D9
Cytoplasmic(Exp)
PITG_06094
Oomycota
Solanum lycopersicum, Solanum tuberosum
Phytophthora infestans
D0N6E1
Cytoplasmic(Exp)
PexRD50(PITG_06099)
Oomycota
Solanum lycopersicum, Solanum tuberosum
Phytophthora infestans
D0N8M5
Cytoplasmic(Exp)
PITG_07555
Oomycota
Solanum lycopersicum, Solanum tuberosum
Phytophthora infestans
D0NB60
Cytoplasmic(Exp)
PITG_09218
Oomycota
Solanum lycopersicum, Solanum tuberosum
Phytophthora infestans
D0NB65
Cytoplasmic(Exp)
CRE9(PITG_09224)
Oomycota
Solanum lycopersicum, Solanum tuberosum
Phytophthora infestans
D0NEV2
Cytoplasmic(Exp)
PITG_10232
Oomycota
Solanum lycopersicum, Solanum tuberosum
Phytophthora infestans
D0NFU7
Cytoplasmic(Exp)
PITG_22926
Oomycota
Solanum lycopersicum, Solanum tuberosum
Phytophthora infestans
D0NIY2
Cytoplasmic(Exp)
PITG_11507
Oomycota
Solanum lycopersicum, Solanum tuberosum
Phytophthora infestans
D0NK98
Cytoplasmic(Exp)
PITG_13093
Oomycota
Solanum lycopersicum, Solanum tuberosum
Phytophthora infestans
D0NL13
Cytoplasmic(Exp)
PITG_12731
Oomycota
Solanum lycopersicum, Solanum tuberosum
Phytophthora infestans
D0NL15
Cytoplasmic(Exp)
PITG_12737
Oomycota
Solanum lycopersicum, Solanum tuberosum
Phytophthora infestans
D0NP16
Cytoplasmic(Exp)
PITG_14783
Oomycota
Solanum lycopersicum, Solanum tuberosum
Phytophthora infestans
D0NP20
Cytoplasmic(Exp)
PITG_14788
Oomycota
Solanum lycopersicum, Solanum tuberosum
Phytophthora infestans
D0NP95
Apoplastic(Exp)
EPIC3
Oomycota
Solanum lycopersicum, Solanum tuberosum
Phytophthora infestans
D0NPQ0
Cytoplasmic(Exp)
CRE16(PITG_23015)
Oomycota
Solanum lycopersicum, Solanum tuberosum
Phytophthora infestans
D0NQ80
Cytoplasmic(Exp)
CRE17(PITG_23042)
Oomycota
Solanum lycopersicum, Solanum tuberosum
Phytophthora infestans
D0NRQ7
Cytoplasmic(Exp)
PITG_15127
Oomycota
Solanum lycopersicum, Solanum tuberosum
Phytophthora infestans
Showing 41 to 60 of 154

List of orthologous identified pathogen effectors

PlantPEAD ID Uniprot ID Localization Pathogen type Species Query proteins
K3X603
Apoplastic(Pre)
Oomycota
Globisporangium ultimum
Q01905
A0A3F2RD02
Apoplastic(Pre)
Oomycota
Phytophthora kernoviae
Q01905
A0A3F2RD05
Apoplastic(Pre)
Oomycota
Phytophthora kernoviae
Q01905
A0A3F2RMK2
Apoplastic(Pre)
Oomycota
Phytophthora kernoviae
Q01905
A0A3F2RNK4
Apoplastic(Pre)
Oomycota
Phytophthora kernoviae
Q01905
A0A3R7GGB2
Apoplastic(Pre)
Oomycota
Phytophthora kernoviae
Q01905
A0A3R7GR59
Apoplastic(Pre)
Oomycota
Phytophthora kernoviae
Q01905
A0A3R7GVV8
Apoplastic(Pre)
Oomycota
Phytophthora kernoviae
Q01905
A0A3R7HM47
Apoplastic(Pre)
Oomycota
Phytophthora kernoviae
Q01905
A0A3R7INW1
Apoplastic(Pre)
Oomycota
Phytophthora kernoviae
Q01905
A0A3R7J734
Apoplastic(Pre)
Oomycota
Phytophthora kernoviae
Q01905
A0A421G3U1
Apoplastic(Pre)
Oomycota
Phytophthora kernoviae
Q01905
A0A662WDR6
Apoplastic(Pre)
Oomycota
Nothophytophthora
Q01905
A0A662WIC8
Apoplastic(Pre)
Oomycota
Nothophytophthora
Q01905
A0A662WJY3
Apoplastic(Pre)
Oomycota
Nothophytophthora
Q01905
A0A662WKR3
Apoplastic(Pre)
Oomycota
Nothophytophthora
Q01905
A0A662WKW9
Apoplastic(Pre)
Oomycota
Nothophytophthora
Q01905
A0A662WLC2
Apoplastic(Pre)
Oomycota
Nothophytophthora
Q01905
A0A662WQW8
Apoplastic(Pre)
Oomycota
Nothophytophthora
Q01905
A0A662WR88
Apoplastic(Pre)
Oomycota
Nothophytophthora
Q01905
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